Gamitrinib TPP hexafluorophosphate

CAS No. 1131626-47-5

Gamitrinib TPP hexafluorophosphate( —— )

Catalog No. M32933 CAS No. 1131626-47-5

Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity, which can regulate cell cycle and cell homeostasis and can be used to study cancer, neurodegenerative diseases and viral infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Gamitrinib TPP hexafluorophosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity, which can regulate cell cycle and cell homeostasis and can be used to study cancer, neurodegenerative diseases and viral infections.
  • Description
    Gamitrinib TPP hexafluorophosphate is aGamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1131626-47-5
  • Formula Weight
    1036.03
  • Molecular Formula
    C52H65F6N3O8P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (48.26 mM; Ultrasonic )
  • SMILES
    O=C(C=C1NC(/C(C)=C\C=C\[C@@H]([C@H](/C(C)=C/[C@H](C)[C@H]([C@@H](OC)C[C@@H](C2)C)O)OC(N)=O)OC)=O)C(NCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=C2C1=O.F[P-](F)(F)(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Markus D. Siegelin, et al. Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells. J Clin Invest. 2011 Apr 1; 121(4): 1349–1360.?
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